(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸
(R)-N-FMOC-(2-Furyl)alanine
CAS: 220497-85-8
Molecular Formula: C22H19NO5
(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸 - Names and Identifiers
| Name | (R)-N-FMOC-(2-Furyl)alanine |
| Synonyms | FMOC-D-2-FURYLALANINE Fmoc-D-2-Furylalanine FMOC-D-ALA(2-FURYL)-OH (R)-N-FMOC-FURYLALANINE FMOC-3-D-ALA(2-FURYL)-OH fmoc-d-3-(2-furyl)-alanine FMOC-3-(2-FURYL)-D-ALANINE Fmoc-3-(2-Furyl)-D-alanine (R)-N-FMOC-(2-FURYL)ALANINE (R)-N-FMOC-(2-Furyl)alanine Fmoc-beta-(2-furyl)-D-Ala-OH FMOC-BETA-(2-FURYL)-D-ALA-OH FMOC-BETA-(2-FURYL)-D-ALANINE N-(9-Fluorenylmethoxycarbonyl)-2-furyl-D-alanine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-furan-2-yl-D-alanine |
| CAS | 220497-85-8 |
| InChI | InChI=1/C22H19NO5/c24-21(25)20(12-14-6-5-11-27-14)23-22(26)28-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/t20-/m1/s1 |
(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸 - Physico-chemical Properties
| Molecular Formula | C22H19NO5 |
| Molar Mass | 377.39 |
| Density | 1.318±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 121.6 °C |
| Boling Point | 505.72°C (rough estimate) |
| Flash Point | 318.6°C |
| Vapor Presure | 2.1E-15mmHg at 25°C |
| Appearance | Powder |
| Color | White to light yellow |
| pKa | 3.62±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5614 (estimate) |
(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29321900 |
(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸 - Introduction
(R)-N-FMOC-(2-Furyl)alanine is a chemical reagent with the following properties:
1. Appearance: White or off-white crystalline solid.
2. Solubility: soluble in some organic solvents such as methanol, ethanol and dichloromethane, insoluble in water.
3. Storage conditions: should be stored in a cool, dry place, avoid direct sunlight.
4. Purity: should have high purity, commonly used in the field of biochemistry and organic synthesis.
(R)-N-FMOC-(2-Furyl)alanine main uses are as follows:
1. Chemical synthesis: As an amino acid protective agent, it is often used to synthesize peptides or proteins by solid phase synthesis.
2. Drug research: It can be used for Peptide Synthesis and structure-activity relationship research in drug research and development.
3. Biochemical research: can be used to analyze the structure and function of biological macromolecules.
The method for preparing (R)-N-FMOC-(2-Furyl)alanine is as follows:
Usually a solid-phase synthesis method is used. First, 2-furylpropionic acid is reacted with (N-9-fluoropropyl) maleimide (Fmoc-Cl) to generate (R)-N-FMOC-(2-Furyl)alanine.
Regarding safety information, the following should be noted:
1. Avoid inhalation or contact with skin and eyes. If contact occurs, rinse immediately with water and seek medical help.
2. In the use of the process to maintain good ventilation, avoid inhalation of dust or solution vapor.
3. Follow proper laboratory procedures to avoid contamination of food, drinking water or cigarettes.
4. Storage should be separated from other chemicals, avoid contact with oxidants.
In addition, comply with local laws and regulations and refer to the safety data sheet provided by the manufacturer.
1. Appearance: White or off-white crystalline solid.
2. Solubility: soluble in some organic solvents such as methanol, ethanol and dichloromethane, insoluble in water.
3. Storage conditions: should be stored in a cool, dry place, avoid direct sunlight.
4. Purity: should have high purity, commonly used in the field of biochemistry and organic synthesis.
(R)-N-FMOC-(2-Furyl)alanine main uses are as follows:
1. Chemical synthesis: As an amino acid protective agent, it is often used to synthesize peptides or proteins by solid phase synthesis.
2. Drug research: It can be used for Peptide Synthesis and structure-activity relationship research in drug research and development.
3. Biochemical research: can be used to analyze the structure and function of biological macromolecules.
The method for preparing (R)-N-FMOC-(2-Furyl)alanine is as follows:
Usually a solid-phase synthesis method is used. First, 2-furylpropionic acid is reacted with (N-9-fluoropropyl) maleimide (Fmoc-Cl) to generate (R)-N-FMOC-(2-Furyl)alanine.
Regarding safety information, the following should be noted:
1. Avoid inhalation or contact with skin and eyes. If contact occurs, rinse immediately with water and seek medical help.
2. In the use of the process to maintain good ventilation, avoid inhalation of dust or solution vapor.
3. Follow proper laboratory procedures to avoid contamination of food, drinking water or cigarettes.
4. Storage should be separated from other chemicals, avoid contact with oxidants.
In addition, comply with local laws and regulations and refer to the safety data sheet provided by the manufacturer.
Last Update：2024-04-09 20:52:54
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View History
(ALPHAR)-ALPHA-[[芴甲氧羰基]氨基]-2-呋喃丙酸
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5 - 溴-1 -乙基- 1H-吡唑
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1-苄基-3-(4-甲氧苯基)-1H-吡唑-4-甲醛
5 - 溴-1 -乙基- 1H-吡唑
ETHYL 1-OXASPIRO[2.5]OCTANE-2-CARBOXYLATE
2-(5-哌啶-4-基-4H-1,2,4-三唑-3-基)吡啶二盐酸盐
4-羟基-6-氯喹啉-3-羧酸乙酯